The comment on OBR rule 8.01(a) clearly states that you can make a pickoff attempt from the windup.
I have never seen this. Does anyone have a video example they can share? Think my son could use it at the youth level (Cal Ripken 11U) to get an unexpected out in a big moment.
But… I feel almost as certain the umps will call a balk, since it is so uncommon and most youth umps still think you must disengage before throwing to a base anyway.